BDBM50034681 2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-[3-(4,4-diphenyl-piperidin-1-yl)-propyl] ester 5-methyl ester::CHEMBL290860

SMILES COC(=[OH+])C1=C(C)N=C(C)C(C1c1ccc(cc1)[N+]([O-])=O)=C([O-])OCCCN1CCC(CC1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=ISZKYBBFFMQCLL-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50034681   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  0.320nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  50nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  210nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  300nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  570nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Synaptic Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50034681(2,6-Dimethyl-4-(4-nitro-phenyl)-1,4-dihydro-pyridi...)
Affinity DataKi:  800nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed