BDBM50035108 3-{4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-butyl}-1H-indole::CHEMBL60267

SMILES Fc1ccc(cc1)C1CCN(CCCCc2c[nH]c3ccccc23)CC1

InChI Key InChIKey=MNTZHLHHOJLERY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50035108   

TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035108(3-{4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-butyl}-1...)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity towards sigma receptor binding site 1 using [3H](+)-pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035108(3-{4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-butyl}-1...)
Affinity DataIC50: 27nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor binding site using [3H]8-OH-DPAT. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035108(3-{4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-butyl}-1...)
Affinity DataIC50: 34nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2A receptor binding site using [3H]ketanserin. More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035108(3-{4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-butyl}-1...)
Affinity DataIC50: 160nMAssay Description:Binding affinity towards Dopamine receptor D2 binding site using [3H]spiroperidol.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed