BDBM50035135 1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro[3,4-dihydro-1H-isochromene-4,4'-(hexahydropyridine)]::CHEMBL63999

SMILES Fc1ccc(cc1)-n1cc(CCCCN2CCC3(CC2)COCc2ccccc32)c2ccccc12

InChI Key InChIKey=MDRDZERYJPALET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035135   

TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035135(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 0.340nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035135(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Affinity DataIC50: 3.40nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed