BDBM50035142 1-[1-(4-fluorophenyl)-1H-3-indolyl]-4-[6-fluorospiro[1,3-dihydroisobenzofuran-1,4'-(hexahydropyridine)]-1-yl]butane::CHEMBL59852

SMILES Fc1ccc(cc1)-n1cc(CCCCN2CCC3(CC2)OCc2ccc(F)cc32)c2ccccc12

InChI Key InChIKey=MVLXAYRBVZMIAU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035142   

TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035142(1-[1-(4-fluorophenyl)-1H-3-indolyl]-4-[6-fluorospi...)
Affinity DataIC50: 0.310nMAssay Description:Binding affinity towards Sigma receptor site 2 in rat brain using [3H]DTG as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50035142(1-[1-(4-fluorophenyl)-1H-3-indolyl]-4-[6-fluorospi...)
Affinity DataIC50: 5.5nMAssay Description:Compound was evaluated for the binding affinity towards Sigma receptor type 1 using radioligand ([3H]-(+)- Pentazocine) binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed