BDBM50035275 5-((3,4,5-trimethoxyphenylamino)methyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::5-[(3,4,5-Trimethoxy-phenylamino)-methyl]-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL69681

SMILES COc1cc(NCc2c[nH]c3nc(N)nc(N)c23)cc(OC)c1OC

InChI Key InChIKey=KYOXMULHHYZUAQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50035275   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035275(5-((3,4,5-trimethoxyphenylamino)methyl)-7H-pyrrolo...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035275(5-((3,4,5-trimethoxyphenylamino)methyl)-7H-pyrrolo...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of Toxoplasma gondii (tc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035275(5-((3,4,5-trimethoxyphenylamino)methyl)-7H-pyrrolo...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Pneumocystis carinii (pc) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035275(5-((3,4,5-trimethoxyphenylamino)methyl)-7H-pyrrolo...)
Affinity DataIC50: 5.63E+4nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50035275(5-((3,4,5-trimethoxyphenylamino)methyl)-7H-pyrrolo...)
Affinity DataIC50: 5.63E+4nMAssay Description:Inhibition of rat liver Dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed