BDBM50035685 CHEMBL2377783

SMILES NS(=O)(=O)c1ccc(CN2C(=O)[C@H]3CC=CC[C@H]3C2=O)cc1

InChI Key InChIKey=DHQMCIMTRYMGID-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50035685   

TargetCarbonic anhydrase 12(Human)
King Saud University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035685BDBM50035685(CHEMBL2377783)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human carbonic anhydrase 12 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
King Saud University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035685BDBM50035685(CHEMBL2377783)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human carbonic anhydrase 9 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
King Saud University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035685BDBM50035685(CHEMBL2377783)
Affinity DataKi:  9.10nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
King Saud University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035685BDBM50035685(CHEMBL2377783)
Affinity DataKi:  34nMAssay Description:Inhibition of human carbonic anhydrase 1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
King Saud University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035685BDBM50035685(CHEMBL2377783)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX2-mediated prostaglandin alpha production by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
King Saud University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035685BDBM50035685(CHEMBL2377783)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX1-mediated prostaglandin alpha production by enzyme immuno assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed