BDBM50035912 CHEMBL3361055

SMILES [#6]-[#6](-[#6])-[#6]-[#7](-[#6]-c1ccccc1C(F)(F)F)S(=O)(=O)c1ccc(\[#6]=[#6]-2/[#6]-[#6]-[#7](-[#6]-[#6]-2)S([#6])(=O)=O)cc1

InChI Key InChIKey=DLTOPWQELBGQRK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035912   

TargetNuclear receptor ROR-gamma(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50035912(CHEMBL3361055)
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]25-hydroxycholesterol from human RORc-LBD expressed in bacterial expression system after 3 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50035912(CHEMBL3361055)
Affinity DataEC50:  75nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain expressed in bacterial expression system assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2016
Entry Details Article
PubMed