BDBM50036041 CHEMBL169887::{(S)-1-[(S)-2-((S)-1-Isopropyl-2,3-dioxo-heptylcarbamoyl)-pyrrolidine-1-carbonyl]-2-methyl-propyl}-carbamic acid benzyl ester

SMILES CCCCC(=O)C(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(C)C

InChI Key InChIKey=DVGSADHIMJFYEW-XWGVYQGASA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036041   

TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036041(CHEMBL169887 | {(S)-1-[(S)-2-((S)-1-Isopropyl-2,3-...)
Affinity DataKi:  1.60nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE) catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala- Ala-Pro-Val-pNMore data for this Ligand-Target Pair
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