BDBM50036059 ((S)-2-Methyl-1-{(S)-2-[(S)-2-methyl-1-(thiazole-2-carbonyl)-propylcarbamoyl]-pyrrolidine-1-carbonyl}-propyl)-carbamic acid benzyl ester::CHEMBL169842::benzyl (S)-1-((S)-2-(((S)-3-methyl-1-oxo-1-(thiazol-2-yl)butan-2-yl)carbamoyl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-ylcarbamate

SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)c1nccs1

InChI Key InChIKey=XTHFEVLNTGTBKU-ACRUOGEOSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50036059   

TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036059(((S)-2-Methyl-1-{(S)-2-[(S)-2-methyl-1-(thiazole-2...)
Affinity DataKi:  270nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE) catalyzed hydrolysis of the synthetic substrate MeO-Suc-Ala- Ala-Pro-Val-pNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036059(((S)-2-Methyl-1-{(S)-2-[(S)-2-methyl-1-(thiazole-2...)
Affinity DataKi:  270nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Zeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036059(((S)-2-Methyl-1-{(S)-2-[(S)-2-methyl-1-(thiazole-2...)
Affinity DataKi:  270nMAssay Description:Inhibition of human neutrophil elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed