BDBM50036255 CHEMBL154197::[(1S,2R)-3-(Benzenesulfonyl-benzyl-amino)-1-benzyl-2-hydroxy-propyl]-carbamic acid benzyl ester

SMILES O[C@H](CN(Cc1ccccc1)S(=O)(=O)c1ccccc1)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=QXXNMHUHYDOUND-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036255   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036255([(1S,2R)-3-(Benzenesulfonyl-benzyl-amino)-1-benzyl...)
Affinity DataKi:  125nMAssay Description:Binding affinity for HIV-1 protease was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036255([(1S,2R)-3-(Benzenesulfonyl-benzyl-amino)-1-benzyl...)
Affinity DataIC50: 190nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed