BDBM50036263 CHEMBL154638::{(1S,2S)-3-[Benzenesulfonyl-(3-methyl-butyl)-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid benzyl ester

SMILES CC(C)CCN(C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=WIDCNHYWIDRDSO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036263   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036263({(1S,2S)-3-[Benzenesulfonyl-(3-methyl-butyl)-amino...)
Affinity DataKi:  295nMAssay Description:Binding affinity for HIV-1 protease was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Searle Discovery Research

Curated by ChEMBL
LigandPNGBDBM50036263({(1S,2S)-3-[Benzenesulfonyl-(3-methyl-butyl)-amino...)
Affinity DataIC50: 450nMAssay Description:Ability to inhibit HIV-1 protease was determined using spectrofluorimetric assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed