BDBM50036329 CHEMBL3353089

SMILES CNc1nc(nn1-c1cccc(c1)C(F)(F)F)-c1ccc(c(OC)c1)-n1cnc(C)c1

InChI Key InChIKey=HATJLUYZMFJYFR-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036329   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50036329(CHEMBL3353089)Copy SMILESCopy InChI

Affinity DataIC50: 280nMAssay Description:Inhibition of human gamma secretase assessed as reduction in Abeta42 levelMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/15/2016
Entry Details Article
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