BDBM50036331 CHEMBL3353091

SMILES COc1cc(ccc1-n1cnc(C)c1)-c1nc(Nc2cccc(OC(F)(F)F)c2)n(C)n1

InChI Key InChIKey=XQMCZHMNJPMERC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50036331   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50036331(CHEMBL3353091)Copy SMILESCopy InChI

Affinity DataIC50: 25nMAssay Description:Inhibition of human gamma secretase assessed as reduction in Abeta42 levelMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/15/2016
Entry Details Article
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