BDBM50036443 4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine::CHEMBL94067

SMILES CC(C)=C1c2ccccc2C=C(C2=CCN(C)CC2)c2ccccc21

InChI Key InChIKey=IFJBEJXBBDCGSC-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50036443   

TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  150nMAssay Description:Affinity was evaluated as inhibition constant for dopamine D-4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  150nMAssay Description:Affinity was evaluated as inhibition constant for dopamine D-4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  270nMAssay Description:Ability to inhibit the binding of [3H]spiperone to the Dopamine receptor D4 in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  520nMAssay Description:Affinity was evaluated as inhibition constant for dopamine D-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  570nMAssay Description:Affinity was evaluated as inhibition constant for dopamine D-2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  570nMAssay Description:Ability to inhibit the binding of [3H]spiperone to the Dopamine receptor D2L in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  830nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  830nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  1.20E+3nMAssay Description:Ability to inhibit the binding of iodine-125-labelled lysergic acid diethylamide([125I]-LSD) to the S-2A serotonin receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  1.50E+3nMAssay Description:Ability to inhibit the binding of iodine-125-labelled lysergic acid diethylamide([125I]-LSD) to the S-2C serotonin receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  2.20E+3nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vanderbilt University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50036443BDBM50036443(4-(5-Isopropylidene-5H-dibenzo[a,d]cyclohepten-10-...)
Affinity DataKi:  2.20E+3nMAssay Description:Affinity was evaluated as inhibition constant for serotonin 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed