BDBM50036901 Benzo[d]isothiazole-3-carboxylic acid {3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-methyl-amide::CHEMBL76110

SMILES COc1ccccc1N1CCN(CCCN(C)C(=O)c2nsc3ccccc23)CC1

InChI Key InChIKey=NXHJZSQUERIEOI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50036901   

Target5-hydroxytryptamine receptor 1A(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036901(Benzo[d]isothiazole-3-carboxylic acid {3-[4-(2-met...)
Affinity DataIC50: 149nMAssay Description:In vitro affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036901(Benzo[d]isothiazole-3-carboxylic acid {3-[4-(2-met...)
Affinity DataIC50: 541nMAssay Description:In vitro affinity towards D2 receptor using [3H]spiroperidol as radioligand in striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036901(Benzo[d]isothiazole-3-carboxylic acid {3-[4-(2-met...)
Affinity DataIC50: 1.65E+3nMAssay Description:In vitro affinity towards 5-hydroxytryptamine 2A receptor using [3H]spiroperidol as radioligand in cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed