BDBM50036902 Benzo[d]isothiazole-3-carboxylic acid {4-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-butyl}-methyl-amide::CHEMBL310261

SMILES CN(CCCCN1CCC(CC1)c1noc2cc(F)ccc12)C(=O)c1nsc2ccccc12

InChI Key InChIKey=RRJGHQGFXIURME-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50036902   

Target5-hydroxytryptamine receptor 2A(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036902(Benzo[d]isothiazole-3-carboxylic acid {4-[4-(6-flu...)
Affinity DataIC50: 13nMAssay Description:In vitro affinity towards 5-hydroxytryptamine 2A receptor using [3H]spiroperidol as radioligand in cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036902(Benzo[d]isothiazole-3-carboxylic acid {4-[4-(6-flu...)
Affinity DataIC50: 72.6nMAssay Description:In vitro affinity towards D2 receptor using [3H]spiroperidol as radioligand in striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036902(Benzo[d]isothiazole-3-carboxylic acid {4-[4-(6-flu...)
Affinity DataIC50: 160nMAssay Description:In vitro affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed