BDBM50036906 Benzo[d]isothiazole-3-carboxylic acid {3-[4-(6-chloro-benzo[d]isoxazol-3-yl)-piperidin-1-yl]-propyl}-amide::CHEMBL77049

SMILES Clc1ccc2c(noc2c1)C1CCN(CCCNC(=O)c2nsc3ccccc23)CC1

InChI Key InChIKey=TZNZWIRUAXXIMC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50036906   

Target5-hydroxytryptamine receptor 2A(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036906(Benzo[d]isothiazole-3-carboxylic acid {3-[4-(6-chl...)
Affinity DataIC50: 115nMAssay Description:In vitro affinity towards 5-hydroxytryptamine 2A receptor using [3H]spiroperidol as radioligand in cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036906(Benzo[d]isothiazole-3-carboxylic acid {3-[4-(6-chl...)
Affinity DataIC50: 739nMAssay Description:In vitro affinity towards D2 receptor using [3H]spiroperidol as radioligand in striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Hoechst-Roussel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036906(Benzo[d]isothiazole-3-carboxylic acid {3-[4-(6-chl...)
Affinity DataIC50: 3.72E+3nMAssay Description:In vitro affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in hippocampusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed