BDBM50036926 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-4H-isoquinoline-1,3-dione::CHEMBL83454

SMILES O=C1Cc2ccccc2C(=O)N1CCCCN1CCN(CC1)c1nsc2ccccc12

InChI Key InChIKey=GVEWBUJRQFIULE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50036926   

Target5-hydroxytryptamine receptor 1A(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036926(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 1.80nMAssay Description:In vitro binding affinity was measured on serotonergic 5-hydroxytryptamine 1A receptor by displacement of [3H]- tetralinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Burroughs Wellcome

Curated by ChEMBL
LigandPNGBDBM50036926(2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-bu...)
Affinity DataIC50: 94nMAssay Description:In vitro binding affinity was measured by displacement of [3H]- raclopride from D2 receptor isolated from the striata of male Dawley ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed