BDBM50037393 5,7-Diamino-2-(3-amino-phenyl)-6-hydroxy-chromen-4-one::CHEMBL325949

SMILES Nc1cccc(c1)-c1cc(=O)c2c(N)c(O)c(N)cc2o1

InChI Key InChIKey=HEQIBPLIDSTDLX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50037393   

TargetEpidermal growth factor receptor(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50037393(5,7-Diamino-2-(3-amino-phenyl)-6-hydroxy-chromen-4...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of in vitro activity of EGFr enzyme from A431 cells in presence of 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50037393(5,7-Diamino-2-(3-amino-phenyl)-6-hydroxy-chromen-4...)
Affinity DataIC50: 3.84E+4nMAssay Description:Inhibition of in vitro protein-tyrosine kinase activity of p60v-src enzyme in presence of 5 uM ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50037393(5,7-Diamino-2-(3-amino-phenyl)-6-hydroxy-chromen-4...)
Affinity DataIC50: 4.60E+4nMAssay Description:In vitro inhibition of protein-tyrosine activity of p56lck enzyme in presence of 50 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed