BDBM50037846 CHEMBL126002::N-tert-Butyl-2-{(3R,5R)-3-[3-(3-chloro-phenyl)-ureido]-7-methyl-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetamide

SMILES Cc1ccc2N(CC(=O)NC(C)(C)C)C(=O)[C@@H](C[C@H](c3ccccc3)c2c1)NC(=O)Nc1cccc(Cl)c1

InChI Key InChIKey=OULXGYXKPKVJPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037846   

TargetGastrin/cholecystokinin type B receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037846(N-tert-Butyl-2-{(3R,5R)-3-[3-(3-chloro-phenyl)-ure...)
Affinity DataIC50: 32nMAssay Description:In vitro affinity to the cholecystokinin type B receptor in guinea pig cortex assayed using [125I]BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037846(N-tert-Butyl-2-{(3R,5R)-3-[3-(3-chloro-phenyl)-ure...)
Affinity DataIC50: 317nMAssay Description:In vitro binding affinity for the cholecystokinin type A receptor in guinea pig pancreas assayed using [125I]BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed