BDBM50037859 CHEMBL333671::N-tert-Butyl-2-{(3R,5R)-8-chloro-3-[3-(3-chloro-phenyl)-ureido]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-acetamide

SMILES CC(C)(C)NC(=O)CN1c2cc(Cl)ccc2[C@H](C[C@@H](NC(=O)Nc2cccc(Cl)c2)C1=O)c1ccccc1

InChI Key InChIKey=PIYVAPZSWIDNTQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037859   

TargetGastrin/cholecystokinin type B receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037859(N-tert-Butyl-2-{(3R,5R)-8-chloro-3-[3-(3-chloro-ph...)
Affinity DataIC50: 6.70nMAssay Description:In vitro affinity to the cholecystokinin type B receptor in guinea pig cortex assayed using [125I]BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037859(N-tert-Butyl-2-{(3R,5R)-8-chloro-3-[3-(3-chloro-ph...)
Affinity DataIC50: 320nMAssay Description:In vitro binding affinity for the cholecystokinin type A receptor in guinea pig pancreas assayed using [125I]BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed