BDBM50037867 CHEMBL126865::N-tert-Butyl-2-{(3R,5R)-3-[3-(3-chloro-phenyl)-ureido]-2-oxo-5-phenyl-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl}-N-methyl-acetamide

SMILES CN(C(=O)CN1c2ccccc2[C@H](C[C@@H](NC(=O)Nc2cccc(Cl)c2)C1=O)c1ccccc1)C(C)(C)C

InChI Key InChIKey=UGINDELNLJSTRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037867   

TargetGastrin/cholecystokinin type B receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037867(N-tert-Butyl-2-{(3R,5R)-3-[3-(3-chloro-phenyl)-ure...)
Affinity DataIC50: 1.5nMAssay Description:In vitro affinity to the cholecystokinin type B receptor in guinea pig cortex assayed using [125I]BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037867(N-tert-Butyl-2-{(3R,5R)-3-[3-(3-chloro-phenyl)-ure...)
Affinity DataIC50: 4.20nMAssay Description:In vitro binding affinity for the cholecystokinin type A receptor in guinea pig pancreas assayed using [125I]BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed