BDBM50037868 CHEMBL127397::N-tert-Butyl-2-[(3R,5R)-2-oxo-5-phenyl-3-(3-m-tolyl-ureido)-2,3,4,5-tetrahydro-benzo[b]azepin-1-yl]-acetamide

SMILES Cc1cccc(NC(=O)N[C@@H]2C[C@H](c3ccccc3)c3ccccc3N(CC(=O)NC(C)(C)C)C2=O)c1

InChI Key InChIKey=ALSNOSFKYCYLJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037868   

TargetGastrin/cholecystokinin type B receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037868(N-tert-Butyl-2-[(3R,5R)-2-oxo-5-phenyl-3-(3-m-toly...)
Affinity DataIC50: 10.1nMAssay Description:In vitro affinity to the cholecystokinin type B receptor in guinea pig cortex assayed using [125I]BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50037868(N-tert-Butyl-2-[(3R,5R)-2-oxo-5-phenyl-3-(3-m-toly...)
Affinity DataIC50: 288nMAssay Description:In vitro binding affinity for the cholecystokinin type A receptor in guinea pig pancreas assayed using [125I]BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed