BDBM50037938 (E)-3-((3S,5R)-8-Methyl-3-phenyl-8-aza-bicyclo[3.2.1]oct-2-yl)-acrylic acid methyl ester::CHEMBL340793

SMILES COC(=O)\C=C\C1C2CC[C@H](C[C@@H]1c1ccccc1)N2C

InChI Key InChIKey=OMLSVYSQLRWXNO-VTVHYWIFSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50037938   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50037938((E)-3-((3S,5R)-8-Methyl-3-phenyl-8-aza-bicyclo[3.2...)
Affinity DataKi:  22nMAssay Description:Binding affinity was determined against cocaine binding site by measuring the ability of compound to displace bound [3H]dopamine from rat caudate-put...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of New Orleans

Curated by ChEMBL
LigandPNGBDBM50037938((E)-3-((3S,5R)-8-Methyl-3-phenyl-8-aza-bicyclo[3.2...)
Affinity DataIC50:  123nMAssay Description:Tested for its ability to inhibit high affinity uptake of [3H]dopamine into rat caudate-putamen tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed