BDBM50037967 CHEMBL3358270

SMILES CCCc1cc(sc1C)C(=O)N[C@H](Cc1ccc(nc1)-c1cccc(OC(F)(F)F)c1)C(=O)N[C@@H]1CCNC1

InChI Key InChIKey=PMTLKNOARSHUJB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50037967   

TargetKinesin-like protein KIFC1(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50037967(CHEMBL3358270)
Affinity DataIC50: 171nMAssay Description:Inhibition of N-terminal His-tagged full length recombinant human HSET assessed as inhibition of microtubule-stimulated ATPase activity incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKinesin-like protein KIFC1(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50037967(CHEMBL3358270)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant N-terminal His6-tagged KIFC1 (Q305-K673 aa) (unknown origin) expressed in Escherichia coli BL21 (DE3) by malachite green as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2016
Entry Details Article
PubMed
TargetKinesin-like protein KIFC1(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50037967(CHEMBL3358270)
Affinity DataIC50: 825nMAssay Description:Inhibition of N-terminal His-tagged full length recombinant human HSET assessed as inhibition of microtubule-stimulated ATPase activity incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKinesin-like protein KIF11(Human)
Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50037967(CHEMBL3358270)
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of GST-tagged Eg5 (unknown origin) assessed as inhibition of microtubule-stimulated ATPase activity incubated for 80 mins in presence of A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed