BDBM50038171 7-Chloro-4-hydroxy-3-[3-(thiophen-3-yloxy)-phenyl]-1H-quinolin-2-one::CHEMBL32076

SMILES O=c1[nH]c2cc(Cl)ccc2c(O)c1-c1cccc(Oc2ccsc2)c1

InChI Key InChIKey=ASDUOZQLLPOESZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50038171   

TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038171BDBM50038171(7-Chloro-4-hydroxy-3-[3-(thiophen-3-yloxy)-phenyl]...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of the binding of [3H]L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed