BDBM50038639 CHEMBL3354856

SMILES Oc1c(cc2ccccc2c1[S+]([O-])c1ccc(F)cc1)-c1cccnc1

InChI Key InChIKey=JOHSRMVJHDHTDQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50038639   

TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University and Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038639BDBM50038639(CHEMBL3354856)
Affinity DataIC50: 33nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University and Helmholtz Institute For Pharmaceutical Research Saarland (Hips)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50038639BDBM50038639(CHEMBL3354856)
Affinity DataIC50: 5.55E+3nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [3H]-11-deoxycorticosterone as substrate after 1 hr by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMed