BDBM50038641 22-cyclopropylmethyl-(2R,13S)-14-oxa-4,22-diazaheptacyclo[13.9.1.01,13.02,21.03,11.05,10.019,25]pentacosa-3(11),5(10),6,8,15,17,19(25)-heptaen-16-ol::CHEMBL418105

SMILES Oc1ccc2C[C@@H]3[C@@H]4c5[nH]c6ccccc6c5C[C@@H]5Oc1c2[C@]45CCN3CC1CC1

InChI Key InChIKey=HQLZRENSDIGHBJ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50038641   

TargetNociceptin receptor(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50038641(22-cyclopropylmethyl-(2R,13S)-14-oxa-4,22-diazahep...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity against delta-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50038641(22-cyclopropylmethyl-(2R,13S)-14-oxa-4,22-diazahep...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity against mu-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50038641(22-cyclopropylmethyl-(2R,13S)-14-oxa-4,22-diazahep...)
Affinity DataKi:  33nMAssay Description:Binding affinity against kappa-opioid receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50038641(22-cyclopropylmethyl-(2R,13S)-14-oxa-4,22-diazahep...)
Affinity DataIC50: 8.20E+3nMAssay Description:Antagonist activity against delta-opioid receptor in mouse vas deferens in the presence of DADLEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed