BDBM50038743 (3S,8R)-3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::(S)-3-[Bis-(4-fluoro-phenyl)-methoxy]-8-methyl-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL294007::ChEMBL_96467

SMILES COC(=O)C1C2CCC(C[C@@H]1OC(c1ccc(F)cc1)c1ccc(F)cc1)N2C

InChI Key

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50038743   

TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50038743(ChEMBL_96467 | (3S,8R)-3-[Bis-(4-fluoro-phenyl)-me...)
Affinity DataIC50: 1.83E+3nMAssay Description:Binding affinity of [3H]citalopram for serotonin transporter in monkeyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50038743(ChEMBL_96467 | (3S,8R)-3-[Bis-(4-fluoro-phenyl)-me...)
Affinity DataIC50: 3.38E+3nMAssay Description:Displacement of [3H]WIN-35428 from monkey dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50038743(ChEMBL_96467 | (3S,8R)-3-[Bis-(4-fluoro-phenyl)-me...)
Affinity DataIC50: 4.93E+3nMAssay Description:Binding affinity of [3H]citalopram for serotonin transporter in monkeyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50038743(ChEMBL_96467 | (3S,8R)-3-[Bis-(4-fluoro-phenyl)-me...)
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity of [3H]citalopram for serotonin transporter in monkeyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50038743(ChEMBL_96467 | (3S,8R)-3-[Bis-(4-fluoro-phenyl)-me...)
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity of [3H]citalopram for serotonin transporter in monkeyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50038743(ChEMBL_96467 | (3S,8R)-3-[Bis-(4-fluoro-phenyl)-me...)
Affinity DataIC50: 8.90E+3nMAssay Description:Displacement of [3H]WIN-35428 from monkey dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50038743(ChEMBL_96467 | (3S,8R)-3-[Bis-(4-fluoro-phenyl)-me...)
Affinity DataIC50: 8.90E+3nMAssay Description:Displacement of [3H]WIN-35428 from monkey dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50038743(ChEMBL_96467 | (3S,8R)-3-[Bis-(4-fluoro-phenyl)-me...)
Affinity DataIC50: 2.19E+4nMAssay Description:Displacement of [3H]WIN-35428 from monkey dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed