BDBM50039636 2,6-Dichloro-benzoic acid 1,1,3-trioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethyl ester::CHEMBL274085

SMILES Clc1cccc(Cl)c1C(=O)OCN1C(=O)c2ccccc2S1(=O)=O

InChI Key InChIKey=BICFHPJPQCDSDL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50039636   

TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50039636(2,6-Dichloro-benzoic acid 1,1,3-trioxo-1,3-dihydro...)
Affinity DataKi:  2nMAssay Description:Observed binding affinity against Human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50039636(2,6-Dichloro-benzoic acid 1,1,3-trioxo-1,3-dihydro...)
Affinity DataKi:  2.70nMAssay Description:In vitro inhibition constant of human leukocyte elastase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50039636(2,6-Dichloro-benzoic acid 1,1,3-trioxo-1,3-dihydro...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article