BDBM50039749 (S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidine::(S)-3-(3-Methanesulfonyl-phenyl)-1-propyl-piperidine::CHEMBL311730

SMILES CCCN1CCC[C@H](C1)c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=GZVBVBMMNFIXGE-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50039749   

TargetD(2) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039749((S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidin...)
Affinity DataKi: >217nMAssay Description:Affinity against recombinant dopamine receptor (DA) D2 expressed in CHO-K1 cells, using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039749((S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidin...)
Affinity DataKi:  447nMAssay Description:In vitro binding affinity against cloned mammalian dopamine D2 autoreceptor, expressed in CHO-K1 cells, using [3H]U-86170 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039749((S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidin...)
Affinity DataKi:  755nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039749((S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidin...)
Affinity DataKi:  1.31E+3nMAssay Description:Tested for in vitro binding affinity against cloned mammalian dopamine D3 receptor, expressed in CHO-K1 cells, using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039749((S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidin...)
Affinity DataKi:  2.59E+3nMAssay Description:Tested for affinity against 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT in homogenized rat brain tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039749((S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidin...)
Affinity DataKi:  3.88E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of G£Teborg

Curated by ChEMBL
LigandPNGBDBM50039749((S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidin...)
Affinity DataKi:  6.27E+3nMAssay Description:Affinity against striatal dopamine D2 receptors using [3H]spiperone as radioligand in rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMed