BDBM50039967 2-(4-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide::CHEMBL95726

SMILES CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccc(cc1)N=C=S

InChI Key InChIKey=HFZVNQMPSGSXHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50039967   

TargetKappa-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50039967(2-(4-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Affinity DataIC50: 14nMAssay Description:Tested for inhibitory concentration against [3H]U-69593 binding at sites kappa-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50039967(2-(4-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Affinity DataIC50: 150nMAssay Description:Tested for inhibitory concentration against [3H]DPDPE binding at sites of delta-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50039967(2-(4-Isothiocyanato-phenyl)-N-methyl-N-((S)-1-phen...)
Affinity DataIC50: 730nMAssay Description:Tested for inhibitory concentration against [3H]DAMGO binding at sites of mu-opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2012
Entry Details Article
PubMed