BDBM50040583 (R)-4-(1,3-Dioxo-5-propoxy-1,3-dihydro-isoindol-2-yl)-2-[(S)-3-methyl-1-((S)-1-methylcarbamoyl-2-phenyl-ethylcarbamoyl)-butylamino]-butyric acid::CHEMBL352232

SMILES CCCOc1ccc2C(=O)N(CC[C@@H](N[C@@H](CC(C)C)C(=O)N[C@@H](Cc3ccccc3)C(=O)NC)C(O)=O)C(=O)c2c1

InChI Key InChIKey=FRRDNYNCIZOSSI-ZNZIZOMTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040583   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040583((R)-4-(1,3-Dioxo-5-propoxy-1,3-dihydro-isoindol-2-...)
Affinity DataIC50:  2.10nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040583((R)-4-(1,3-Dioxo-5-propoxy-1,3-dihydro-isoindol-2-...)
Affinity DataIC50:  427nMAssay Description:Activity against human stromelysin (MMP-3).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040583((R)-4-(1,3-Dioxo-5-propoxy-1,3-dihydro-isoindol-2-...)
Affinity DataIC50:  15nMAssay Description:Activity against human collagenase (MMP-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed