BDBM50040607 (R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl)-2-{(S)-1-[(S)-2-(4-hydroxy-phenyl)-1-methylcarbamoyl-ethylcarbamoyl]-3-methyl-butylamino}-butyric acid::CHEMBL351968

SMILES CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)N[C@H](CCN1C(=O)c2cc3ccccc3cc2C1=O)C(O)=O

InChI Key InChIKey=OMXCPVVQAGTBGJ-PVHODMMVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50040607   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040607((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50:  3.80nMAssay Description:Activity against human gelatinase (MMP-9).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040607((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50:  29nMAssay Description:Activity against human collagenase (MMP-1).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Glaxo Inc. Research Institute

Curated by ChEMBL
LigandPNGBDBM50040607((R)-4-(1,3-Dioxo-1,3-dihydro-benzo[f]isoindol-2-yl...)
Affinity DataIC50:  72nMAssay Description:Activity against human stromelysin (MMP-3).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed