BDBM50040728 CHEMBL3353219::US9255110, 1

SMILES NCC1CCN(CC1)c1ccc(Cl)cc1NC(=O)c1cnn2cc(O)cnc12

InChI Key InChIKey=BNVZRFQNZWYPQH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50040728   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM50040728(CHEMBL3353219 | US9255110, 1)
Affinity DataIC50:  1nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Roche Palo Alto

US Patent
LigandPNGBDBM50040728(CHEMBL3353219 | US9255110, 1)
Affinity DataIC50:  1nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040728(CHEMBL3353219 | US9255110, 1)
Affinity DataIC50:  55nMAssay Description:Inhibition of IRAK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Nimbus Discovery

Curated by ChEMBL
LigandPNGBDBM50040728(CHEMBL3353219 | US9255110, 1)
Affinity DataIC50:  55nMAssay Description:Purified recombinant IRAK-4 protein was incubated with 250 uM synthetic peptide(KKARFSRFAGSSPSQSSMVAR) in 30 ul of kinase buffer including (20 mM MOP...More data for this Ligand-Target Pair
In DepthDetails US Patent