BDBM50040928 4-[6-(4-cyanoanilino)-1,3-dioxo-2,3-dihydro-1H-5-isoindolylamino]benzonitrile::CHEMBL267869

SMILES O=C1NC(=O)c2cc(Nc3ccc(cc3)C#N)c(Nc3ccc(cc3)C#N)cc12

InChI Key InChIKey=KQTHJPWPAZKUSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50040928   

TargetEpidermal growth factor receptor(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040928(4-[6-(4-cyanoanilino)-1,3-dioxo-2,3-dihydro-1H-5-i...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-dependent protein kinase(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040928(4-[6-(4-cyanoanilino)-1,3-dioxo-2,3-dihydro-1H-5-i...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory activity was determined against protein kinase A (PKA) of rabbitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed