BDBM50041025 CHEMBL3355410

SMILES CC1(C)N[C@H]([C@H](c2cccc(Cl)c2F)[C@]11C(=O)Nc2cc(Cl)ccc12)C(=O)N[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=OWIHIJVRYXBFOS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50041025   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50041025(CHEMBL3355410)
Affinity DataKi:  19nMAssay Description:Binding affinity to human His-tagged MDM2 (1 to 118 residues) using FAM tagged p53-based peptide by fluorescence prolarization based protein binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan Comprehensive Cancer Center and Departments of Internal Medicine

Curated by ChEMBL
LigandPNGBDBM50041025(CHEMBL3355410)
Affinity DataIC50: 151nMAssay Description:Binding affinity to human His-tagged MDM2 (1 to 118 residues) using FAM tagged p53-based peptide by fluorescence prolarization based protein binding ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed