BDBM50041086 CHEMBL3355430
SMILES OC(=O)c1ccc(NC(=O)[C@@H]2NC3(CCCCC3)[C@]3([C@H]2c2cccc(Cl)c2F)C(=O)Nc2cc(Cl)ccc32)cc1
InChI Key InChIKey=BIDSEXPFIMKDMF-LOLKONATSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50041086
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataKi: 0.160nMAssay Description:Binding affinity to human His-tagged MDM2 (1 to 118 residues) using FAM tagged p53-based peptide by fluorescence prolarization based protein binding ...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Displacement of PMDM6-F fluorescent probe from human recombinant His-tagged MDM2 (1 to 118 residues) after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
University Of Michigan Comprehensive Cancer Center And Departments Of Internal Medicine
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Binding affinity to human His-tagged MDM2 (1 to 118 residues) using FAM tagged p53-based peptide by fluorescence prolarization based protein binding ...More data for this Ligand-Target Pair