BDBM50041520 1,3-PROPYLENE-BIS-N,N''-SYN-4-PYRIDINIUMALDOXIME::Bispyridinium oxime(TMB)::CHEMBL32778::CHEMBL426113

SMILES O=NCc1cc[n+](CCC[n+]2ccc(CN=O)cc2)cc1

InChI Key InChIKey=PRWZSCZFNNWUSR-UHFFFAOYSA-N

Data  2 IC50  3 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50041520   

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50041520(1,3-PROPYLENE-BIS-N,N''-SYN-4-PYRIDINIUMALDOXIME |...)
Affinity DataKd:  1.45E+5nMAssay Description:Reactivation of tabun-inhibited recombinant human AChE measured up to 10 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50041520(1,3-PROPYLENE-BIS-N,N''-SYN-4-PYRIDINIUMALDOXIME |...)
Affinity DataKd:  4.78E+4nMAssay Description:Reactivation of paraoxon-inhibited recombinant human AChE measured up to 10 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50041520(1,3-PROPYLENE-BIS-N,N''-SYN-4-PYRIDINIUMALDOXIME |...)
Affinity DataIC50:  1.67E+5nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50041520(1,3-PROPYLENE-BIS-N,N''-SYN-4-PYRIDINIUMALDOXIME |...)
Affinity DataIC50:  2.57E+6nMAssay Description:Inhibition of human acetylcholinesterase by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(GUINEA PIG)
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50041520(1,3-PROPYLENE-BIS-N,N''-SYN-4-PYRIDINIUMALDOXIME |...)
Affinity DataEC50: >1.00E+6nMAssay Description:Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscarinic acetylcholne receptor M2 of pig heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Strasburg

Curated by ChEMBL
LigandPNGBDBM50041520(1,3-PROPYLENE-BIS-N,N''-SYN-4-PYRIDINIUMALDOXIME |...)
Affinity DataKd:  7.90E+4nMAssay Description:Reactivation of tabun-inhibited human acetylcholinesterase assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed