BDBM50041919 6-{4-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-phenyl}-3,4-dihydro-2H-pyrimido[2,1-a]isoquinoline::CHEMBL106521

SMILES COc1cc(CCc2ccc(cc2)C2=Cc3ccccc3C3=NCCCN23)cc(OC)c1OC

InChI Key InChIKey=PHOYZGLRYUFZJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50041919   

TargetPlatelet-activating factor receptor(Human)
Sandoz Research Institute

Curated by ChEMBL
LigandPNGBDBM50041919(6-{4-[2-(3,4,5-Trimethoxy-phenyl)-ethyl]-phenyl}-3...)
Affinity DataIC50: 40nMAssay Description:In vitro PAF antagonistic activity by determining [3H]PAF binding to the PAF-receptor of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed