BDBM50041934 5-Methyl-6-(3,4,5-trimethoxy-benzyl)-thieno[2,3-d]pyrimidine-2,4-diamine::5-methyl-6-(3,4,5-trimethoxybenzyl)thieno[2,3-d]pyrimidine-2,4-diamine::6-(3,4,5-trimethoxybenzyl)-5-methylthieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL322315

SMILES COc1cc(Cc2sc3nc(N)nc(N)c3c2C)cc(OC)c1OC

InChI Key InChIKey=XUIJYXWWCHQIJA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50041934   

TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041934(6-(3,4,5-trimethoxybenzyl)-5-methylthieno[2,3-d]py...)
Affinity DataIC50: 630nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041934(6-(3,4,5-trimethoxybenzyl)-5-methylthieno[2,3-d]py...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041934(6-(3,4,5-trimethoxybenzyl)-5-methylthieno[2,3-d]py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041934(6-(3,4,5-trimethoxybenzyl)-5-methylthieno[2,3-d]py...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed