BDBM50041936 6-(3,4-Dichloro-phenyl)-5-methyl-thieno[2,3-d]pyrimidine-2,4-diamine::CHEMBL107167

SMILES Cc1c(sc2nc(N)nc(N)c12)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=YJQGTWXFPZUEAF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50041936   

TargetDihydrofolate reductase(Lactobacillus casei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041936(6-(3,4-Dichloro-phenyl)-5-methyl-thieno[2,3-d]pyri...)
Affinity DataIC50: 2.00E+3nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041936(6-(3,4-Dichloro-phenyl)-5-methyl-thieno[2,3-d]pyri...)
Affinity DataIC50: 4.60E+3nMAssay Description:Tested for inhibitory activity against dihydrofolate reductase in Beef liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041936(6-(3,4-Dichloro-phenyl)-5-methyl-thieno[2,3-d]pyri...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041936(6-(3,4-Dichloro-phenyl)-5-methyl-thieno[2,3-d]pyri...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50041936(6-(3,4-Dichloro-phenyl)-5-methyl-thieno[2,3-d]pyri...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed