BDBM50041957 CHEMBL3358935
SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2cc(ncc2[nH]1)N1CCOCC1)C(F)(F)F
InChI Key InChIKey=QGPHIACZTUTSAR-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50041957
Affinity DataIC50: 2nMAssay Description:Displacement of RU-486 from GR (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Displacement of tetramethylrhodamine-labeled dexamethasone from PR (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+3nMAssay Description:Displacement of RU-486 from MR (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CYP3A4 using 7-benzyloxy-4-(trifluoromethyl)-coumarin as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Agonist activity at GR in HFF cells assessed as suppression of IL-1-induced IL-6 productionMore data for this Ligand-Target Pair