BDBM50041962 (+)-Trifluoro-methanesulfonic acid 3-(1-propyl-piperidin-3-yl)-phenyl ester::CHEMBL110821

SMILES CCCN1CCC[C@@H](C1)c1cccc(OS(=O)(=O)C(F)(F)F)c1

InChI Key InChIKey=VUEGBGWRCATKQZ-UHFFFAOYSA-N

Data  6 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50041962   

TargetSigma non-opioid intracellular receptor 1(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041962((+)-Trifluoro-methanesulfonic acid 3-(1-propyl-pip...)
Affinity DataIC50: 6nMAssay Description:Binding effinity for sigma receptor using 2 nM of [3H]DTG as radioligand, in membranes from brain minus cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041962((+)-Trifluoro-methanesulfonic acid 3-(1-propyl-pip...)
Affinity DataKi: >933nMAssay Description:Binding towards dopamine receptor D4 expressed in CHO-K1 cells using [3H]spiperone More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041962((+)-Trifluoro-methanesulfonic acid 3-(1-propyl-pip...)
Affinity DataKi: >1.62E+3nMAssay Description:Binding towards Dopamine receptor D3 expressed in CHO-K1 cells using [3H]spiperone More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041962((+)-Trifluoro-methanesulfonic acid 3-(1-propyl-pip...)
Affinity DataKi: >1.68E+3nMAssay Description:Evaluated for binding towards Dopamine receptor D2 using [3H]N-0437 as radioligand from rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041962((+)-Trifluoro-methanesulfonic acid 3-(1-propyl-pip...)
Affinity DataKi: >2.00E+3nMAssay Description:Binding towards Dopamine receptor D2 expressed in CHO-K1 cells using [3H]U-86170More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041962((+)-Trifluoro-methanesulfonic acid 3-(1-propyl-pip...)
Affinity DataKi:  5.60E+3nMAssay Description:Evaluated for binding towards dopamine D2-receptor using [3H]N-0437 as radioligand from rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of GöTeborg

Curated by ChEMBL
LigandPNGBDBM50041962((+)-Trifluoro-methanesulfonic acid 3-(1-propyl-pip...)
Affinity DataKi:  8.30E+3nMAssay Description:Binding towards Dopamine receptor D2 using [3H]spiperone from rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed