BDBM50042428 CHEMBL116863::[3-Methyl-1-(1-propylaminooxalyl-propylcarbamoyl)-butyl]-carbamic acid benzyl ester

SMILES CCCNC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1

InChI Key InChIKey=VAHBSYHWRRVRNN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50042428   

TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042428(CHEMBL116863 | [3-Methyl-1-(1-propylaminooxalyl-pr...)
Affinity DataKi:  250nMAssay Description:Compound was evaluated for the inhibition of Cysteine protease Calpain 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042428(CHEMBL116863 | [3-Methyl-1-(1-propylaminooxalyl-pr...)
Affinity DataKi:  250nMpH: 8.0Assay Description:Inhibitory activity of alpha-keto esters towards calpain 2 at pH 8.0More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042428(CHEMBL116863 | [3-Methyl-1-(1-propylaminooxalyl-pr...)
Affinity DataKi:  8.00E+3nMpH: 5.2Assay Description:Inhibition of alpha-keto esters towards cathepsin B at pH 5.2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Bos taurus (bovine))
Georgia Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50042428(CHEMBL116863 | [3-Methyl-1-(1-propylaminooxalyl-pr...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed