BDBM50042990 (E)-3-(3'',4''-Dihydroxyphenyl)-1-(3',4',5'-trimethoxyphenyl)prop-2-en-1-one::(E)-3-(3,4-Dihydroxy-phenyl)-1-(3,4,5-trimethoxy-phenyl)-propenone::3,4-dihydroxy-3',4',5'-trimethoxychalcone::3-(3,4-Dihydroxy-phenyl)-1-(3,4,5-trimethoxy-phenyl)-propenone::3-(3,4-dihydroxyphenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-en-1-one::CHEMBL126617

SMILES COc1cc(cc(OC)c1OC)C(=O)\C=C\c1ccc(O)c(O)c1

InChI Key InChIKey=YRADLNGHQMLFDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50042990   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Tokushima Bunri University

Curated by ChEMBL
LigandPNGBDBM50042990(3-(3,4-dihydroxyphenyl)-1-(3,4,5-trimethoxyphenyl)...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibition against 5-lipoxygenase in RBL-1 cells was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTubulin beta-1 chain(Human)
University of Salford

Curated by ChEMBL
LigandPNGBDBM50042990(3-(3,4-dihydroxyphenyl)-1-(3,4,5-trimethoxyphenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed