BDBM50043090 1N-[2-hydroxy-7,7-dimethyl-1-spiro[1H-indene-1,4'-(hexahydropyridine)]-1-ylsulfonylmethyl-(1S,2R,4R)-bicyclo[2.2.1]hept-2-ylmethyl]-2-amino-(2S)-pentanediamide::CHEMBL130848

SMILES CC1(C)[C@@H]2CC[C@@]1(CS(=O)(=O)N1CCC3(CC1)C=Cc1ccccc31)[C@@](O)(CNC(=O)[C@@H](N)CCC(N)=O)C2

InChI Key InChIKey=JFORQSJIEQRPEO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50043090   

TargetOxytocin receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043090(1N-[2-hydroxy-7,7-dimethyl-1-spiro[1H-indene-1,4'-...)
Affinity DataIC50: 90nMAssay Description:Tested against rat uterine OT receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V1a/V1b receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043090(1N-[2-hydroxy-7,7-dimethyl-1-spiro[1H-indene-1,4'-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of radioligand [3H]AVP binding to the vasopressin V1 receptor in rat liver tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50043090(1N-[2-hydroxy-7,7-dimethyl-1-spiro[1H-indene-1,4'-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of radioligand [3H]-AVP binding to the vasopressin V2 receptor in rat kidney tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed