BDBM50043647 CHEMBL3355532

SMILES CC(=O)N1Cc2cc(Nc3ncc4c(n3)n3ccnc3n(-c3ccccc3Cl)c4=O)ccc2C2(CC2)C1

InChI Key InChIKey=WJRROINZDMTREW-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50043647   

TargetWee1-like protein kinase(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50043647(CHEMBL3355532)
Affinity DataKi:  5.40nMAssay Description:Inhibition of GST-tagged human Wee1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50043647(CHEMBL3355532)
Affinity DataEC50:  620nMAssay Description:Inhibition of human Weel1 in human NCI-H1299 cells assessed as phosphorylation of Cdk1 after overnight incubation by ELISA PD assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed