BDBM50044071 3-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(E)-ylidene]-5-mercapto-3,4-dihydro-pyrrol-2-one::CHEMBL113211

SMILES CC(C)(C)c1cc(\C=C2/CC(=S)NC2=O)cc(c1O)C(C)(C)C

InChI Key InChIKey=IESQOZLTQCTSSB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50044071   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50044071(3-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(E)...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calcium ionophore A-23187More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed