BDBM50044150 CHEMBL3314010

SMILES CC(C)C[C@H]1C[C@H](C1)c1onc([C@@H](CC(O)=O)CC(=O)Nc2ccc(C)cc2Cl)c1C1CC1

InChI Key InChIKey=PNHNAYPNWQHBLI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50044150   

TargetNuclear receptor ROR-gamma(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50044150(CHEMBL3314010)
Affinity DataEC50:  43nMAssay Description:Inhibition of GAL4 DNA-binding domain fused RORgamma (unknown origin) transfected in CHO-K1 cells incubated for 2 days by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Japan Tobacco

Curated by ChEMBL
LigandPNGBDBM50044150(CHEMBL3314010)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human RoRc-LBD expressed in CHO cells assessed as transcriptional activity by GAL4 reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2016
Entry Details Article
PubMed